Bisflex CF Tablet

Bisflex CF Tablet is a herbal-nutraceutical combination formulated specifically for fracture healing acceleration and bone strength restoration. When speed of fracture healing is a concern — whether following orthopaedic surgery, traumatic fracture, or stress fractures in osteoporotic patients — Bisflex CF provides a scientifically supported, natural adjunct to conventional orthopaedic management.

The formulation combines the bone-healing properties of Cissus quadrangularis with the anti-inflammatory potency of Curcumin, the superior calcium delivery of Calcium Citrate Malate, and the bone-mineralization directing effects of Vitamins K2 and D3 — five ingredients working in concert to accelerate bone repair at every stage of the healing cascade.

The Role of Each Ingredient

Cissus Quadrangularis Extract — 700 mg
Known traditionally as “the bone setter,” Cissus quadrangularis is one of the most extensively studied herbs for bone healing. It contains anabolic steroids (ketosteroids), ascorbic acid, carotenoids, and calcium — all of which contribute to its bone-regenerative properties. Clinically, it has been shown to accelerate fracture healing by stimulating osteoblast activity and collagen synthesis, reducing healing time significantly compared to placebo.

Curcumin — 100 mg
Curcumin is the active polyphenol from Turmeric with well-documented anti-inflammatory, antioxidant, and osteogenic properties. In the context of fracture healing, inflammation control is critical — excessive or prolonged inflammation delays the transition from the inflammatory phase to the repair and remodelling phases of bone healing. Curcumin moderates this inflammatory response while also stimulating osteoblast differentiation.

Calcium (as Calcium Citrate Malate) — 150 mg
The foundational mineral for bone matrix formation. Calcium Citrate Malate is the most bioavailable form of calcium — absorbed effectively with or without food and without interfering with other mineral absorptions. In fracture healing, adequate calcium delivery is essential for callus formation and bone mineralization.

Vitamin K2 (MK-7) — 22.5 MCG
Vitamin K2 activates osteocalcin — the protein responsible for binding calcium into the bone matrix. Without adequate K2, calcium may be absorbed but not effectively deposited into healing bone tissue. K2 also prevents arterial calcification, ensuring that supplemental calcium goes where it is needed — into bones, not blood vessels.

Vitamin D3 — 400 IU
Vitamin D3 is the essential regulator of calcium metabolism — enhancing intestinal calcium absorption and ensuring adequate serum calcium levels for bone mineralisation during the healing process.

The Fracture Healing Cascade — How Bisflex CF Intervenes

• Inflammatory Phase (Days 1–5): Curcumin moderates excessive inflammation, enabling faster transition to repair
• Soft Callus Formation (Days 5–14): Cissus quadrangularis stimulates osteoblast activity and collagen synthesis for callus development
• Hard Callus / Mineralisation (Weeks 2–6): Calcium Citrate Malate + Vitamin D3 + K2 ensure adequate calcium deposition into the hardening callus
• Remodelling Phase (Weeks 6+): Continued K2 and D3 support optimal bone density restoration in the remodelled tissue

Clinical Indications

• Post-fracture management — accelerating bone union
• Post-orthopaedic surgery recovery — supporting surgical bone repair
• Osteoporotic fractures — providing the nutritional foundation for healing in compromised bone
• Stress fractures in athletes and active individuals
• Adjunct to immobilisation therapy — maintaining bone health during cast or fixation periods
• Delayed fracture union — where standard healing timelines are not being met

Key Clinical Advantages

• First herbal combination specifically targeting fracture healing speed
• Cissus quadrangularis — clinically proven to reduce fracture healing time
• Curcumin controls the inflammatory phase — enabling faster progression to repair
• Calcium Citrate Malate — most bioavailable calcium form for bone mineralisation
• K2 ensures calcium is directed into bone tissue, not arteries
• D3 maximises calcium absorption for effective delivery to healing bone
• Natural, herbal-nutraceutical approach — suitable for long-term use

Composition